UniProt is the universal protein resource, a central repository of protein data created by combining Swiss-Prot, TrEMBL and PIR. This makes it the world’s most comprehensive resource on protein information.
UniProt provides four core database:
* The UniProt Knowledgebase (UniProtKB) is the central database of protein sequences with accurate, consistent, and rich sequence and functional annotation.
* The UniProt Reference Clusters (UniRef) databases provide non-redundant reference data collections based on the UniProt knowledgebase in order to obtain complete coverage of sequence space at several resolutions.
* The UniProt Metagenomics and Environmental Sequences database (UniMES) is a repository specifically developed for metagenomic and environmental sequence data.
* The UniProt Archive (UniParc) provides a stable, comprehensive sequence collection without redundant sequences by storing the complete body of publicly available protein sequence data.
This video tutorial gives an overview of the UniProt bioinformatics website. To show its practical application, the human protein college is researched, its amino acid sequence is discovered, and the blastp tool is used to BLAST the protein to find organisms having collagen with similarity.
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